Agenda

Sunday,  March 31

 
Reception (6 pm)  
Plenary lecture (7 pm)  
Emilio Carbone  L-type calcium channels in pacemaking, secretion and autism viewed through mouse models
Opening dinner (8 pm)  
   
   

Monday, April 1

 
Channelopathies (8:30 am):  
Terry Snutch P/Q-type channels: splicing, synapses and spreading depolarization 
Tuck Wah Soong Calcium-dependent facilitation of Cav2.1 channel and ataxia
Philippe Lory New Cav3 channelopathies
Ivy Dick Calcium channel deficits underlying cardiac arrhythmias: from mechanisms to therapy
Jeff Noebels Isolating minimal brain circuitry of mutant calcium channel epilepsies
Ivana Souza Short talk: R-type calcium channel mutations in pediatric epilepsy patients
   
Neurophysiology:  
Anjali Rajadhyaksha Impact of Cav1.2 channel deficiency in the prefrontal cortex on social behavior 
Heesup Shin Thalamic low threshold bursts in control of fear memory
Roger Thompson Pannexin-1 channels as critical mediators of non-ionotropic NMDAR dependent LTD
Arn van den Maagdenberg Cav2.1 channels in disease: from mutations to models and shared mechanisms
Jing Zhai Short talk: Deletion of IQ-domain RNA editing in Cav1.3 channel enhances spatial learning and memory
   
   

Tuesday, April 2

 
Calcium channels and pain (8:30 am):  
Gerald Zamponi Calcium dysregulation during chronic pain
David Adams Analgesic α-conotoxins targeting neuronal calcium channels directly and via GPCR activation
Atsufumi Kawabata Distinct effects of T-type Ca2+ channel blockers and genetic deletion of Cav3.2 on somatic and visceral hypersensitivity
Jin Tao Methylation of miRNA contributes to trigeminal neuralgia by regulating Cav3.2 expression
Mike Hildebrand Contributions of T-type channels towards spinal pain processing
Norbert Weiss Homocysteinemia in pain processing – a role for T-type channels
Emmanuel Bourinet Spinal Cav3.2 T-type channels modulates sensory and affective related symptoms of neuropathic pain
Maria Gandini Short talk: Splice variant dependent opiod receptor modulation of N-type calcium channels
Synaptic physiology:  
Dick Tsien Calcium channels and unconventional synaptic signaling
Luyang Wang Functional modules of voltage-gated calcium channels in gating transmitter release
William Catterall Calcium channel regulation, synaptic plasticity, and spatial learning
   
   

Wednesday, April 3

 
Subunits/protein complexes (8:30 am):  
Annette Dolphin Studies on the mechanism of action of auxiliary alpha2delta subunits
Gerald Obermair/Stefanie Geisler Presynaptic α2δ subunits of voltage-gated calcium channels regulate synaptic connectivity
David Luo In vitro characterization of aberrant sensory neuron synapse formation involving voltage gated calcium channel α2δ-1 subunit proteins
Manua Ben-Johny Allosteric modulation of Cav channels by stac proteins 
Filip van Petegem Structural insights into the binding and regulation of L-type calcium channels by calmodulin and STAC proteins
Ray Turner FMRP as a constituent member of the Cav3-Kv4 complex
Gary Stephens Modulation of T-type calcium channels by the CACHD1 protein
Marta Campiglio Short talk: STAC3 – the missing link in skeletal muscle excitation-contraction coupling
Giriraj Sahu Short talk: Cav1.3 forms a tri-protein complex to drive the slow AHP in hippocampal pyramidal cells
Hadhi Asmara Short talk: A dynamic T-type-Calmodulin interaction activates aCaMKII and CREB
   
Cardiovascular physiology:  
Livia Hool The role of the L-type calcium channel and extracellular matrix stiffness in the regulation of cardiac metabolic activity
Matteo Mangoni Functional role of L-type Cav1.3 channels in adrenergic regulation of cardiac pacemaker activity
   
   

Thursday, April 4

 
Calcium signaling (8:30 am):  
Stefan Herlitze Optogenetic control and visualization of changes in intracellular calcium levels. 
Mark Shapiro Synergistic interplay between various calcium-permeable ion channels direct nervous function in brain and peripheral neurons
Peter Stys Axonal Ca dynamics and the axo-myelinic synapse
   
Distribution/expression:  
Elizabeth (Liz) Tunbridge The diversity of Cav1.2 isoforms in human brain
Akos Kulik Differential subcellular distribution and regulatory role of Cav1 and Cav2 channels in hippocampal neurons
Miguel Martin-Caraballo Post-transcriptional regulation of Cav3.2 T-type calcium channel subunit by interleukin-6 in prostate cancer cells: role of miR-32
Mario Giocobassi Using Ca Imaging to functionally differentiate between neuronal subclasses.
Baldomero Olivera Defining voltage gated Ca channel expression in different DRG neuronal subclasses
Olena Fedorenko Short talk: Expression of voltage-dependent calcium channels in adipocytes
Nneoma Akaniro-Ejim Short talk: Characterisation and functional regulation of lL-type calcium channels in white fat adipocytes
   
Reception (6 pm)  
Conference dinner (7 pm)  
   
   

Friday, April 5

 
Pharmacology/gating (8:30 am):  
Steffen Hering On the link between activation and inactivation in Cav1.2
Richard Lewis ω-conotoxin interactions at N-type Cavs
Henry Colecraft Towards more precise Cav channel inhibitors
Arnaud Monteil Setting up a functional assay to search for modulators of neuronal sodium leak channels (NALCN)
Slobodan Todorovic Different roles of T-type calcium channel isoforms in neurosteroid anesthesia
Toru Ogawa Short talk: Drug discovery research for novel Cav3.2 channel antagonists
   
Neurodevelopment/neurodegeneration:  
James Surmeier Cav1 calcium channels link regenerative activity to bioenergetic control in neurons
Brigit Liss Voltage gated calcium channels in Parkinsons disease
Stephen Ferguson Sex-specific differences in mGluR5 signaling in AD mouse models
Yong Li DUSP6 SUMOylation protects cells from oxidative damage via direct regulation of Drp1 dephosphorylation
Sean Cregan Short talk: Regulation of ER-mitochondrial calcium dynamics and neuronal cell death by Bcl-family proteins
Nadine Ortner Short talk: Cav1.3 L-type calcium channels in neurodevelopmental disorders