Second International Calcium Channel Conference
Placencia, Belize – March 28 to April 3, 2010
Program
Sunday, March 28:
Welcome Reception
Keynote lecture
William Catterall, PhD – “Calcium Channel Regulation in Synaptic Plasticity and the Fight-or-Flight Response”
Monday, March 29:
Calcium channel physiology
Terrance Snutch, PhD – “Calcium-dependent modulation of P/Q-type calcium channels is altered by Familial Hemiplegic Migraine Type-1 mutations and in a Cav2.1 splice-dependent manner”
Daniela Pietrobon, PhD – “Differential effect of hemiplegic migraine mutations in the P/Q-type Ca2+ channel on cortical excitatory and inhibitory synaptic transmission”
Hee-Sup Shin, PhD – “Observational fear learning by empathy involves affective pain system and Cav1.2 Ca2+ channels in the anterior cingulate cortex”
Emmanuel Bourinet, PhD – “Direct functional coupling between the CaV3.2 T-type calcium channel and nitric oxide synthase contributes to nociception”
Paula Barrett, PhD – “Spontaneous electrical firing of mouse adrenal zona glomerulosa cells: role of Cav3.2 channels.”
Peter Stys, MD – “Internodal Ca permeable channels: implications for axonal degeneration”
Leanne Cribbs, PhD – “Regulation of T-type Calcium Channels in Pulmonary Hypertension and Ventricular Remodeling”
Ricardo Dolmetsch, PhD – “Using iPSC derived neurons to study the cellular basis of Timothy syndrome, a multisystemic disorder associated with autism”
Tuesday, March 30:
Calcium channel interactions/regulation
Gerald Zamponi, PhD – “Regulation of calcium channels by the ERAD complex”
Daniel Minor, PhD – “Structural and functional investigation of multiple Ca2+/CaM binding sites on the Cav1.2 C‑terminal tail uncovers a role in channel facilitation and no evidence for dimer formation”
Annette Dolphin, PhD – “Calcium channel α2δ subunits: GPI-anchoring, trafficking and mechanism of action of gabapentinoid drugs”
Ray Turner, PhD – “Cav3 calcium channels link to the Kv4 channel complex to control neuronal output”
Emilio Carbone, PhD – “Role of Cav1.3 and fast inactivating BK channel coupling in pacemaking mouse chromaffin cells”
Kevin Currie, PhD – “Activity-dependent inhibition of N-type calcium channels: a novel PKC-independent effect of phorbol esters”
Wednesday, March 31:
Calcium channel gating
Kurt Beam, PhD – “Voltage- and calcium-dependent inactivation of Cav1.2, but not of Cav2.1, is suppressed in skeletal muscle”
Stefan Herzig, PhD – “Single channel manifestations of L-type calcium channel inactivation”
Steffen Hering, PhD – “Gating determinants in L-type (CaV1.2) channels”
Alexandra Koschak, PhD – “Impact of protein interactions for gating modulation of Cav 1.3 L-type calcium channels”
Edward Perez-Reyes, PhD – “Characterization of the gating brake in the I-II loop of CaV3 T-type Ca2+ channels”
Slobodan Todorovic, MD, PhD – “Glycosylation alters gating and inactivation of T-type calcium channels in the pain pathway”
Thursday, April 1:
Gene transcription and posttranslational modification
Diane Lipscombe, PhD – “Cell-specific alternative splicing in N-type calcium channels controls their sensitivity to G protein coupled receptors”
Tuck Wah Soong, PhD – “Post-transcriptional modification modulates CaV channel function”
Zhong-Ping Feng, PhD – “Gene expression and functional L-type calcium channel”
Data Blitz:
Stuart Cain (Cav3.2 + burst firing in GAERS); Summer Allen (Fox-2 and N-type splice regulation); Laura Roberts (β subunit control of localization); Thomas Helton (Microtubule proteins and N-type); Osvaldo Uchitel (FHM-1 and Cav 2.1)
Reception & Dinner
Friday, April 2:
Pharmacology
Osvaldo Uchitel, PhD – “Intrinsic activation/inactivation parameters of CaV2.1 calcium channels are shifted by Pregabalin, modulating neurotransmitter release”
Elizabeth Tringham, PhD – “Novel T-type blockers identified in CaV3.2 state-dependent fluorescent assay effectively suppress seizures”
Z. David Luo, PhD – “Mechanism of calcium channel α2δ-1 subunit mediated neuropathic pain”
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